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It is a medical device that is used for disposable syringes for humans or animals to prevent repeated use. The safety syringe consists of a storage bag, a needle, and a needle guard. When in use, the needle protection sleeve is cut along the parallel direction of the needle, the protective sleeve is pulled out of the needle for injection, and the protective sleeve is reset after the injection, so that the needle is no longer wounded, thereby achieving the purpose of one-time anti-reuse. The protective sleeve cuts the limited position of the blade for the special attachment, and in any case, it is easy to cut the protective sleeve. Protective cover and needle combination without storage bag can be used with other types of syringes.